Chemical constituents in the roots of Salvia przewalskii Maxim.
- Author:
Wan-sheng CHEN
1
;
Xin-ming JIA
;
Wei-dong ZHANG
;
Zi-yang LOU
;
Chuan-zhuo QIAO
Author Information
- Publication Type:Journal Article
- MeSH: Heterocyclic Compounds, 4 or More Rings; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Oleanolic Acid; chemistry; isolation & purification; Plant Roots; chemistry; Plants, Medicinal; chemistry; Quinones; chemistry; isolation & purification; Salvia; chemistry; Triterpenes; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2003;38(5):354-357
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo investigate the chemical composition of the root of Salvia przewalskii Maxim.
METHODSCompounds were isolated by silica gel column chromatography. Structures of these compounds were elucidated by spectral analysis (EI-MS, FAB-MS, 1HNMR, 13CNMR, 1H-1H COSY, 1H-13C COSY, HMBC, NOESY) and phytochemical properties.
RESULTSEight compounds were isolated and identified as: tanshinone II-A (I), crypotanshinone (II), przewaquinone A (III), sugiol (IV), ursolic acid (V), 2 alpha, 3 alpha-dihydroxy urs-12-ene-28-acid (VI), oleanolic acid (VII), and neo-przewaquinone A (VIII).
CONCLUSIONCompound VIII is a new compound, and compound II, IV, V, VI and VII are isolated from this plant for the first time.
