Voltammetric behaviors of diethylstilbestrol and its determination at multi-wall carbon nanotubes modified glassy carbon electrode.
- Author:
Yan-yi SUN
1
;
Kang-bing WU
;
Sheng-shui HU
Author Information
- Publication Type:Journal Article
- MeSH: Carbon; chemistry; Diethylstilbestrol; analysis; chemistry; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Nanotechnology
- From: Acta Pharmaceutica Sinica 2003;38(5):364-367
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo fabricate multi-wall carbon nanotube (MWNT) modified electrode and study the electrochemical behaviors of diethylstilbestrol at the MWNT-modified electrode.
METHODSCyclic voltammetry and linear sweep voltammetry.
RESULTSThe oxidation peak current of diethylstilbestrol increased remarkably and the peak potential shifted negatively at the MWNT-dihexadecyl hydrogen phosphate (DHP) modified glassy carbon electrode (GCE), in contrast to that at the bare GC electrode and DHP-modified GC electrode. The oxidation peak current is linear with the concentration of diethylstilbestrol over the range from 1 x 10(-8) to 2 x 10(-6) mol.L-1. The detection limit was 2.5 x 10(-9) mol.L-1. The relative standard deviation (n = 10) was 2.9% for 1 x 10(-6) mol.L-1 diethylstilbestrol.
CONCLUSIONThe MWNT-DHP modified GCE exhibits catalytic activity to the oxidation of diethylstilbestrol.
