Effect of Candida albicans growth on silicone elastomer containing nano-TiO2.
- Author:
Bei LI
1
;
Yi-Min ZHAO
;
Ju-Cai YANG
;
Ying HAN
;
Zhi-Wei DONG
Author Information
- Publication Type:Journal Article
- MeSH: Antifungal Agents; pharmacology; Candida albicans; drug effects; Nanostructures; Silicone Elastomers; chemistry; pharmacology; Titanium; pharmacology
- From: Chinese Journal of Stomatology 2008;43(6):367-369
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the antibacterial effect against Candida albicans of the A-2186 silicone elastomer containing nano-TiO2 in vitro.
METHODSAntibacterial agent of nano-TiO2 was added into A-2186 silicone elastomer with incorporating percentages of 0.5%, 1.0%, 1.5%, and 2.0% (W/W). There was no nano-TiO2 in the control group. The antibacterial effect of the A-2186 silicone elastomer was determined using the film contact method with lighting and without lighting.
RESULTSEither with lighting or without lighting, there were significances between the experiment groups and the control group (P < 0.05). When the incorporating percent was 2.0%, the inhibitory effect was the best among the experiment groups. Without lighting, the inhibitory rate was 53.7% and with lighting, the inhibitory rate was 85.9%.
CONCLUSIONSThe A-2186 silicone elastomer containing nano-TiO2 has antibacterial properties against Candida albicans, which enhances with increases of nano-TiO2 percent in the material. With the same incorporating percentage, the antibacterial effect with lighting is better than that without lighting.
