Clinical application of positron-emission tomography for the identification of cervical nodal metastases of head and neck caner compared with CT or MRI and clinical palpation
10.3321/j.issn:1002-0098.2008.12.001
- VernacularTitle:正电子发射体层摄影术诊断头颈部恶性肿瘤颈部淋巴结转移的临床价值探讨
- Author:
Zhong-Wei CHEN
1
;
Li-Jun ZHU
;
Qing-Yi HOU
;
Qi-Peng WANG
;
Sui JIANG
;
Hang FENG
Author Information
1. 广东省人民医院
- Keywords:
Positron-emission tomography;
Head and neck neoplasms;
Lymphatic metastasis
- From:
Chinese Journal of Stomatology
2008;43(12):705-708
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of positron-emission tomography(PET)for the identification of cervical nodal metastases of head and neck cancer compared with CT/MRI and clinical palpation.Methods Forty patients of head and neck cancer Lulderwent PET and CT/MRI examination 2 weeks before surgery.PET,CT/MRI and clinical palpation were interpreted separately to assess regional lymph node status.Histopathologic analysis was used as the gold standard for assessment of the lymph node involvement.Differences in sensitivity.specificity and accuracy among the imaging modalities and clinical palpation were analyzed.Results The sensitivity of PET for the identification of nodal metastases was 14.3% highor than that of CT/MRI (P=0.648)and 14.3% higher than that of clinical palpation(P=0.648),whereas the specificity of PET was 15.4% higher than that of CT/MRI(P=0.188)and 7.7% higher than that of clinical palpation(P=0.482).The accuracy of 18F-FDG PET,CT/MRI,and clinical palpation for the identifieation of cervical nodal metastases was 85.0%,70.0% and 75.0% respectively.Conclusions The sensitivity,specificity and accuracy of PET for the detection of cervical nodal metastases was higher than that of CT/MRI and clinical palpation.Although the results did not show a statistically significant difference,PET can still serve as a supplementary method for the identification of nodal metastases of head and neck cancer.
