Radiation-induced maxillary malignancies: complications of radiotherapy treatment for head-neck malignant tumors.
- Author:
Jian-Ning WANG
1
;
Ru-Yao LI
;
Min-Yi CUI
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Female; Head and Neck Neoplasms; radiotherapy; Humans; Incidence; Jaw Neoplasms; etiology; Male; Middle Aged; Neck; diagnostic imaging; Neoplasms, Radiation-Induced; Osteoradionecrosis; etiology; Radiography; Radiotherapy; adverse effects; Retrospective Studies; Young Adult
- From: Chinese Journal of Stomatology 2008;43(12):713-715
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the incidence of radiation-induced maxillary malignancy after radiotherapy for head and neck cancer.
METHODSA total of 273 patients who suffered from osteoradionecrosis after radiotherapy for head and neck cancer were evaluated. Among them, 6 patients were presented with carcinoma and sarcoma arising from maxillary area after radiotherapy.
RESULTSRadiation-induced maxillary cancers happened at a rate of 2.2% in the patients with osteoradionecrosis. There were no statistically significant differences in age, sex and the time interval between the radiotherapy and the cancer occurrence.
CONCLUSIONSRadiation-induced malignancy after radiotherapy for head and neck cancer is mainly located in maxilla, presenting as squamous cell carcinoma or sarcoma of the maxillary sinus.