Minor new constituents from Heteroplexis micocephala.
- Author:
Xiao-Na FAN
1
;
Sheng LIN
;
Cheng-Gen ZHU
;
Yong-Chun YANG
;
Jian-Gong SHI
Author Information
1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education of PRC, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Aster Plant;
chemistry;
Benzofurans;
chemistry;
isolation & purification;
Diterpenes;
chemistry;
isolation & purification;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Naphthalenes;
chemistry;
isolation & purification;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2010;45(1):82-86
- CountryChina
- Language:English
-
Abstract:
By using a combination of various chromatographic techniques including column chromatography over silica gel and Pharmadex LH-20 and reversed-phase HPLC, two minor new compounds, labda-12, 14-dien-6beta, 7alpha, 8beta, 17-tetraol (1), 2, 3-cis-6-acetyl-5-hydroxy-2-(hydroxymethylvinyl)-2, 3-dihydrobenzofuran-3-ol angelate (2), and a minor new natural product 6-methoxy-4-methyl-3, 4-dihydro-2H-naphthalen-1-one (3) have been isolated from an ethanolic extract of Heteroplexis micocephala. Their structures were elucidated with spectroscopic data analysis including 2D NMR experiments.
