A new chromone derivative from Berchemia lineata.
- Author:
Yu-xia SHEN
1
;
Hong-li TENG
;
Guang-zhong YANG
;
Zhi-nan MEI
;
Xiao-long CHEN
Author Information
1. College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China.
- Publication Type:Journal Article
- MeSH:
Catechin;
analogs & derivatives;
chemistry;
isolation & purification;
Chromones;
chemistry;
isolation & purification;
Flavanones;
chemistry;
isolation & purification;
Flavonoids;
chemistry;
isolation & purification;
Molecular Structure;
Plant Roots;
chemistry;
Plants, Medicinal;
chemistry;
Quercetin;
analogs & derivatives;
chemistry;
isolation & purification;
Rhamnaceae;
chemistry
- From:
Acta Pharmaceutica Sinica
2010;45(9):1139-1143
- CountryChina
- Language:English
-
Abstract:
To study the chemical constituents from the root of Berchemia lineata (L.) DC., nine compounds were isolated from the EtOAc extract by using silica gel, RP-C18 silica gel column chromatography and preparative HPLC. Based on the spectroscopic analysis, their structures were identified as 5-hydroxy-7-(2'-hydroxypropyl)-2-methyl-chromone (1), (-)-(1'R, 2'S)-erythro-5-hydroxy-7-(1', 2'-dihydroxypropyl)-2-methyl-chromone (2), naringenin (3), eriodictyol (4), (+)-aromadendrin (5), (+)-taxifolin (6), (+)-catechin (7), (+)-epigallocatechin (8) and quercetin (9). Among them, compound 2 is a new chromone derivative. Compound 1 is a known chromone derivative and isolated from this genus for the first time. Compounds 3-9 are known flavonoids and isolated from this plant for the first time.