Advances in novel anti-HIV-1 drugs and drug candidates: 2005-2008.
- Author:
Pu-rong ZHENG
1
;
Hai XUE
;
Zhi-yan XIAO
;
Gang LIU
Author Information
1. Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Acquired Immunodeficiency Syndrome;
drug therapy;
Anti-HIV Agents;
chemistry;
pharmacology;
therapeutic use;
HIV Fusion Inhibitors;
chemistry;
pharmacology;
therapeutic use;
HIV Infections;
drug therapy;
HIV Integrase Inhibitors;
chemistry;
pharmacology;
therapeutic use;
HIV Protease Inhibitors;
chemistry;
pharmacology;
therapeutic use;
HIV-1;
drug effects;
Humans;
Molecular Structure;
Reverse Transcriptase Inhibitors;
chemistry;
pharmacology;
therapeutic use
- From:
Acta Pharmaceutica Sinica
2010;45(2):154-164
- CountryChina
- Language:Chinese
-
Abstract:
HIV and AIDS remain as the crucial global health concern, therefore, research and development of novel anti-HIV-1 chemical therapeutics is still of paramount significance, which may be illuminated by cases of successful marketed drugs. Herein, we document the discovery and biological profile of new anti-HIV-1 drugs approved by FDA between 2005 and 2008 and some drug candidates are also discussed.
