A Case of Fungal Keratitis Scedosporium apiospermum.
10.3341/jkos.2013.54.4.675
- Author:
Saem LEE
1
;
Dong Wook LEE
;
Hye Soo LEE
;
In Cheon YOU
Author Information
1. Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea. you2ic@paran.com
- Publication Type:Case Report
- Keywords:
Corneal ulcer;
Fungal keratitis;
Scedosporium apiospermum;
Voriconazole
- MeSH:
Amphotericin B;
Anti-Bacterial Agents;
Antifungal Agents;
Aza Compounds;
Corneal Ulcer;
Eye;
Fluconazole;
Gardening;
Humans;
Keratitis;
Plants;
Pyrimidines;
Quinolines;
Scedosporium;
Soil;
Triazoles;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2013;54(4):675-679
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of fungal keratitis caused by Scedosporium apiospermum. CASE SUMMARY: A 70-year-old man visited our clinic with complaints of redness and decreased visual acuity in his right eye caused by a soil gotten into an eye while gardening 10 days ago. The patient had previously been treated in a local clinic but did not show significant clinical improvement. Bacterial and fungal staining, culture, and an antibiotic sensitivity test were performed from a corneal scrape. The cultures revealed growth of Scedosporium apiospermum. The patient was treated with topical moxifloxacin antibiotics, fluconazole, amphotericin B antifungal agents. However, the lesion was not improved, so antifungal therapy was switched to topical voriconazole. After two months of treatment, the infection was resolved with mild scarring. CONCLUSIONS: Although it is a rare pathogen, Scedosporium apiospermum should be considered as a potential pathogen in patients presenting with corneal ulceration due to trauma from an object contaminated by soil, polluted water, or spoiled plant contact. And we suggest that topical application of voriconazole may be a good alternative treatment for patient with fungal keratitis in which no improvement despite a conventional antifungal agent, fluconazole.
