Clinical study on intrauterine hemorrhagic fever with renal syndrome virus infection.
- Author:
Huabin PENG
1
;
Shuyun TANG
;
Xiuling QI
Author Information
- Publication Type:Journal Article
- MeSH: Female; Fetal Blood; immunology; Fetal Diseases; virology; Follow-Up Studies; Hantaan virus; immunology; Hemorrhagic Fever with Renal Syndrome; blood; transmission; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; blood; virology
- From: Chinese Journal of Experimental and Clinical Virology 2002;16(3):281-282
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo find out the status of intrauterine infection with hemorrhagic fever with renal syndrome virus (HFRSV).
METHODSThe blood of mothers and the umbilical cords were examined by using anti-HFRSV-IgG at labor of mothers infected with HFRSV. The venous blood of naturally delivered babies were examined for anti-HFRSV-Ig M, HI test was used to type the HFRSV.
RESULTSMothers blood showed positive reaction for anti-HFRSV-IgG. Twenty-three of 27 cases of the fetal death were umbilical cords blood positive two out of twelve of umbilical cord blood that the babies were born naturally after their mothers recovered showed positive for anti-HFRSV -IgG but negative for anti-HFRSV-IgM, 14 babies born naturally normally.
CONCLUSIONSHFRSV can cause intrauterine infection, and lead to fetal death, but no post natal deformity was observed in the babies born naturally.
