Studies on terpenoids from Zygophyllum fabago.
- Author:
Jiang-ho HE
;
Yan-fen NIU
;
Jin-xian LI
;
Lin-bo WANG
;
Tai-ping ZI
;
Shan YU
;
Jian TAO
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Molecular Structure;
Spectrometry, Mass, Electrospray Ionization;
Terpenes;
chemistry;
isolation & purification;
Zygophyllum;
chemistry
- From:
China Journal of Chinese Materia Medica
2015;40(23):4634-4638
- CountryChina
- Language:Chinese
-
Abstract:
This study was to investigate the chemical constituents of the aerial part of Zygophyllumfabago, by phytochemical methods. The compounds were isolated by silica gel and Sephadex LH-20 column chromatographies from the EtOAc extract. Their structures were characterized by various spectroscopic data (1H-NMR, 13C-NMR, MS) and comparison with the literature. As a result, thirteen compounds were isolated and their structures were identified as 1-hydroxyhinesol(1), hinesol(2), atractylenolactam(3), beta-eudesmol (4), 5alpha-hydroperoxy-beta-eudesmol(5), 12-hydroxy-valenc-1(10)-en-2-one(6), pubinernoid A(7), (6S,7E)-6-hydroxy-4,7-megastigmadien-3,9-dione(8), 3-hydroxy-5alpha, 6alpha-epoxy-beta-ionone (9), (3S,5R, 6S, 7E)-3, 5, 6-trihydroxy-7-megastigmen-9-one(10), (6R,7E,9R)-9-hydroxy-4,7-megastigmadien-3-one(11), (S)-3-hydroxy-beta-ionone(12), and blumenol A(13). Compounds 1-7 were sesquiterpenoids and 8-13 were megastigmane type norsesquiterpenoids. All the compounds were obtained from Z. fabago for the first time, and compound 1 was a new natural product.
