Initial CT-guided percutaneous biopsy of vertebral lesions: Evaluation of its diagnostic accuracy and clinical value.
10.1007/s11596-015-1472-8
- Author:
Wen-Bin HUA
1
;
Qiang WU
;
Bo ZHANG
;
Shu-Hua YANG
;
Zeng-Wu SHAO
;
Wei-Hua XU
;
Ye WANG
;
Xu-Dong ZHANG
Author Information
1. Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China, huawb1987@163.com.
- Publication Type:Journal Article
- MeSH:
Biopsy, Needle;
methods;
Diagnosis, Differential;
Humans;
Radiography, Interventional;
adverse effects;
methods;
Reproducibility of Results;
Retrospective Studies;
Sensitivity and Specificity;
Spinal Diseases;
diagnosis;
Tomography, X-Ray Computed;
adverse effects;
methods
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2015;35(4):569-573
- CountryChina
- Language:English
-
Abstract:
This study aimed to examine the diagnostic accuracy and clinical efficacy of initial CT-guided percutaneous biopsy of the vertebral lesions. A total of 305 percutaneous biopsies of the vertebral lesions were performed under either CT guidance (n=127) or C-arm guidance (n=178). The diagnostic accuracy rate was evaluated by comparing the histopathological diagnosis with the ultimate diagnosis. The histopathological diagnosis was consistent with the ultimate diagnosis in 108 (85.0%, 108/127) cases of CT-guided biopsy and in 135 (75.8%, 135/178) cases of C-arm guided biopsy and there was a significant difference. The accuracy of diagnosis based on biopsies varied with different diseases, including primary benign or malignant tumors, metastatic tumors, inflammatory lesions and fractures. A second biopsy or further examinations were required for patients with negative result obtained in the initial biopsy. The complication rate was 3.1% (4/127) in CT-guided biopsy and 7.3% (13/178) in C-arm guided biopsy. In conclusion, CT-guided percutaneous biopsy is an accurate and safe technique for biopsy of the vertebral lesions.
