Right ventricular outflow tract septal pacing versus apical pacing: A prospective, randomized, single-blind 5-years follow-up study of ventricular lead performance and safety.
10.1007/s11596-015-1518-y
- Author:
Yuan-hong LIANG
1
;
Lie LIU
2
;
Dong-li CHEN
3
;
Chun-ying LIN
3
;
Hong-wen FEI
3
;
Si-lin CHEN
4
;
Shu-lin WU
5
Author Information
1. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medicine Science, Guangzhou, 510100, China. eliangyh@163.com.
2. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medicine Science, Guangzhou, 510100, China. lie_liu@hotmail.com.
3. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medicine Science, Guangzhou, 510100, China.
4. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medicine Science, Guangzhou, 510100, China. doctorchensilin@126.com.
5. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medicine Science, Guangzhou, 510100, China. doctorwushulin@163.com.
- Publication Type:Journal Article
- Keywords:
follow-up;
lead performance;
right ventricular outflow tract setptum septal pacing
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Female;
Follow-Up Studies;
Heart Septum;
physiopathology;
Heart Ventricles;
physiopathology;
Humans;
Male;
Middle Aged;
Pacemaker, Artificial;
Single-Blind Method
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2015;35(6):858-861
- CountryChina
- Language:English
-
Abstract:
Lead placement for ventricular pacing variably impacts the physiological benefit of the patient. This study evaluated the ventricular lead performance and safety of right ventricular outflow tract septal pacing in patients with bradyarrhythmia in South China over 60-month follow-up. Totally, 192 patients (108 males, and 84 females, 63±21 years old) with bradyarrhythmia were randomly divided into two groups. The right ventricular outflow tract septum (RVOTs) group had lead placement near the septum (n=97), while the right ventricular apex (RVA) group had a traditional apical placement (n=95). RV septal lead positioning was achieved with a specialized stylet and confirmed using fluoroscopic projection. All patients were followed up for 60 months. Follow-up assessment included stimulation threshold, R-wave sensing, lead impedance and lead complications. The time of electrode implantation in both the ROVTs and RVA groups were significantly different (4.29±0.61 vs. 2.16±0.22 min; P=0.009). No differences were identified in threshold, impedance or R-wave sensing between the two groups at 1st, 12th, 36th and 60th month during the follow-up period. No occurrence of electrode displacement, increased pacing threshold or inadequate sensing was found. The long-term active fixation ventricular electrode performance in RVOTs group was similar to that in RVA group. RVOTs pacing near the septum using active fixation electrodes may provide stability during long-term follow-up period.
