A Case of Hemophagocytic Lymphohistiocytosis in a Child with Systemic Lupus Erythematosus.
- Author:
Ja Young HWANG
1
;
Suk Man NO
;
Jin LEE
;
Pil Sang JANG
;
Young Hoon KIM
;
Jin Tack KIM
;
Joon Sung LEE
Author Information
1. Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. jintackk@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Hemophagocytic lymphohistiocytosis;
Systemic lupus erythematosus
- MeSH:
Adjustment Disorders;
Autoimmune Diseases;
Bone Marrow;
Child*;
Histiocytes;
Humans;
Liver Diseases;
Lupus Erythematosus, Systemic*;
Lymphohistiocytosis, Hemophagocytic*;
Mononuclear Phagocyte System;
Pancytopenia
- From:Journal of the Korean Pediatric Society
2003;46(10):1029-1031
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hemophagocytic lymphohistiocytosis is a reactive disorder characterized by a generalized non-malignant histiocytic proliferation with prominent hemophagocytosis by stimulated histiocytes in the bone marrow and reticuloendothelial systems resulting in pancytopenia and liver dysfunction. Several diseases including infection, malignancy and autoimmune disease are known to be causative disorders. This case demonstrated histiocytic hemophagocytosis in the bone marrow, resulting in pancytopenia during treatment of systemic lupus erythematosus and did not show any underlying disease.
