Effect of periodontitis on circulating C-reactive protein in type 2 diabetes patients.
- Author:
Yu-xin GU
1
;
Qing-xing LI
;
Yan-ling YOU
;
Guang-shun LIU
;
Xu HAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Periodontitis
- From: West China Journal of Stomatology 2006;24(5):435-437
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of periodontal infection on circulating C-reactive protein (CRP) in type 2 diabetes patients.
METHODS32 diabetes patients with advanced periodontitis participated in this study. They were compared to a group of 32 diabetes patients without periodontal disease, who were mathed with regard to age (+/- 3 years), gender and body mass index (+/- 1 kg/m2). The concentration of CRP on circulation was measured by ELISA.
RESULTSSignificant difference was found in the level of CRP and the percentage of subjects with elevated CRP levels > or = 3 mg/L on circulation between the two groups(P < 0.05).
CONCLUSIONPeriodontal infection results in higher circulating CRP in type 2 diabetes patients. This elevated inflammatory factor may exacerbate insulin resistance and increase the risk for great vessels complications of diabetes mellitus.
