Congenital adrenal hyperplasia masquerading as periodic paralysis in an adolescent girl.
- Author:
Anjali SATHYA
1
;
R GANESAN
;
Arun KUMAR
Author Information
1. Department of Endocrinology, Vijaya Hospital, 175, NSK Salai, Saligramam, Vadapalani, Chennai 600026, Tamil Nadu, India. anjalisathyab@yahoo.co.in
- Publication Type:Case Reports
- MeSH:
Adolescent;
Adrenal Hyperplasia, Congenital;
diagnosis;
genetics;
Alkalosis;
diagnosis;
Diagnosis, Differential;
Female;
Humans;
Hypertension;
diagnosis;
Hypokalemia;
diagnosis;
Models, Biological;
Paralysis;
diagnosis;
Sexual Infantilism;
diagnosis;
Steroid 21-Hydroxylase;
metabolism
- From:Singapore medical journal
2012;53(7):e148-9
- CountrySingapore
- Language:English
-
Abstract:
Congenital adrenal hyperplasia is an uncommon diagnosis in routine clinical practice. 21-hydroxylase deficiency, which is its most common subtype, may be diagnosed at birth in a female infant by virilisation or by features of salt wasting in both genders. However, other uncommon subtypes of this condition such as 17-alpha-hydroxylase deficiency, 11-beta-hydroxylase deficiency may present much later in adolescence or adulthood. A high index of suspicion is necessary when evaluating children with hypertension, hypokalaemia, metabolic alkalosis or sexual infantilism.
