Influence of stretch strain and pressure on expression of osteoblasts' FOS protein.
- Author:
Xizheng ZHANG
1
;
Yong GUO
;
Reixin LI
;
Yunshan ZHAO
;
Jimin WU
;
Jing GUAN
Author Information
1. Institute of Military Medical Equipment, Academy Military Medical Sciences, Tianjin 300161, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Animals, Newborn;
Cell Proliferation;
Cells, Cultured;
Osteoblasts;
cytology;
metabolism;
Proto-Oncogene Proteins c-fos;
biosynthesis;
genetics;
Rats;
Rats, Wistar;
Skull;
cytology;
Tensile Strength
- From:
Journal of Biomedical Engineering
2006;23(2):326-328
- CountryChina
- Language:Chinese
-
Abstract:
Uniaxial stretch strain and compressive pressure of 2 atm were applied to rat's osteoblasts, and then immunohistochemistrical staining was used to detect the expression of osteoblasts' c-fos gene. The experiment result indicated the osteoblasts' FOS proteins increased prominently, and the FOS proteins concentrated in nucleolus after having endured two different kinds of loadings. It is very important to prompt stress and strain in promoting osteoblast proliferation.
