Computer simulation methods of cardiac electrophysiology.
- Author:
Yinbin JIN
1
;
Lin YANG
;
Hong ZHANG
;
Yezhuo HUANG
;
Dazong JIANG
Author Information
1. College of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
- Publication Type:Journal Article
- MeSH:
Algorithms;
Computer Simulation;
Electrocardiography;
Electrophysiology;
Heart Ventricles;
cytology;
Humans;
Models, Cardiovascular;
Myocytes, Cardiac;
physiology;
Software;
Ventricular Function
- From:
Journal of Biomedical Engineering
2006;23(2):419-423
- CountryChina
- Language:Chinese
-
Abstract:
Computer simulation is one of the powerful protocols to study electrophysiology theoretically. In this paper,the algorithm of Rush and Larsen was used to solve the ordinary differential equations (ODE's) in the Luo-Rudy models of mammalian ventricular cell. The operator splitting and adaptive time step methods were used to solve the partial differential equations (PDE's) in cardiac tissue conduction models. Using these methods we accomplished the simulation programs of single ventricular cell model and two-dimensional (2-D) tissue model. The methods of initiating spiral waves were studied with this software. The data obtained from 2-D simulation can be used for further study on isopotential contour lines, spiral wave tip trajectories, and pseudo-ECG.
