Compliance of small diameter polyurethane artificial vascular graft .
- Author:
Shirong PAN
1
;
Jun TAO
;
Huanling ZHENG
;
Wu YI
Author Information
1. The 1st Affilliated Hospital, Zhong Shan University, Guangzhou 510080, China. gzpshr@163.com
- Publication Type:Journal Article
- MeSH:
Biocompatible Materials;
chemistry;
Blood Vessel Prosthesis;
Compliance;
Elasticity;
Humans;
Polyurethanes;
chemistry
- From:
Journal of Biomedical Engineering
2006;23(3):517-520
- CountryChina
- Language:Chinese
-
Abstract:
The radical compliance of small diameter artificial vascular grafts was measured by a device made of laser micrometer, pressure transducer, A/D card, micro computer and pulsed circulation loop, the volumetric compliance was measured by a device made of micro-syringe and pressure transducer; the longitudinal compliance was calculated from volumetric compliance and radical compliance. The research results showed that the radical compliance, volumetric compliance and longitudinal compliance would rise not only with the increase in polyurethane (PU) elasticity and salt/polymer ratio (or porosity), but also with the decrease in dipping layers (or wall thickness). Circumferential moduli E zeta and longitudinal moduli E theta could be calculated from volumetric compliance and longitudinal compliance respectively; E theta and E zeta would decrease with the increase in PU elasticity and salt/polymer ratio, but was independent on number of dipping layers. Small diameter PU artificial vascular grafts with compliance close to natural vein or artery can be prepared by choosing of more elastic PU materials (Chro or PCU1500), optimization of salt/polymer ratio (6:1), and the number of dipping layers (4-6 layers).
