Methodological assessment and bias estimation of two serum procalcitonin analysis systems.
- Author:
Xiaona ZHOU
1
;
Ailin WANG
;
Shuyan SUN
Author Information
- Publication Type:Journal Article
- MeSH: Bias; Blood Chemical Analysis; methods; Calcitonin; blood; Calcitonin Gene-Related Peptide; Humans; Protein Precursors; blood
- From: Journal of Southern Medical University 2014;34(5):683-685
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the comparability and bias of the test results of two detection systems for serum procalcitonin (PCT) under the same laboratory condition.
METHODSAccording to the profile NCCLS-EP9-A, the two systems were used to detect PCT to obtain the correlation coefficient and the liner equation for evaluation of the test result bias.
RESULTS AND CONCLUSIONThe test results of PCT showed no significant difference between the two detection systems (P>005) with a kappa value greater than 0.75. The correlation coefficients of both systems were above 0.975, suggesting a consistency between them for clinical detection of PCT.