Statistical properties of nucleotide clusters in DNA sequences.
- Author:
Jun CHENG
1
;
Lin-Xi ZHANG
Author Information
1. Department of Physics, Jinhua University, Jinhua 321017, China. Jh_Chengjun@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Base Composition;
Base Sequence;
Chromosomes;
genetics;
DNA, Protozoan;
genetics;
Genome, Protozoan;
Genomics;
Nucleotides;
genetics;
Plasmodium falciparum;
genetics
- From:
Journal of Zhejiang University. Science. B
2005;6(5):408-412
- CountryChina
- Language:English
-
Abstract:
Using the complete genome of Plasmodium falciparum 3D7 which has 14 chromosomes as an example, we have examined the distribution functions for the amount of C or G and A or T consecutively and non-overlapping blocks of m bases in this system. The function P(S) about the number of the consecutive C-G or A-T content cluster conforms to the relation P(S) proportional, variante(-alphas); values of the scaling exponent alpha(CG) are much larger than alpha(AT); and alpha(AT) of 14 chromosomes are hardly changed, whereas alpha(CG) of 14 chromosomes have a number of fluctuations. We found maximum value of A-T cluster size is much larger than C-G, which implies the existence of large A-T cluster. Our study of the width function xi(m) of cluster C-G content showed that follows good power law xi(m) proportional, variantm(-gamma). The average gamma for 14 chromosomes is 0.931. These investigations provide some insight into the nucleotide clusters of DNA sequences, and help us understand other properties of DNA sequences.
