Distribution of hepatitis B virus genotype B subgenotype in China.
- Author:
Yue-hua HUANG
1
;
Bin ZHOU
;
Zhan-hui WANG
;
Shi-wu MA
;
Min-feng LIANG
;
Jin-lin HOU
Author Information
- Publication Type:Journal Article
- MeSH: China; DNA, Viral; genetics; Genotype; Hepatitis B; virology; Hepatitis B virus; classification; genetics; isolation & purification; Humans; Phylogeny; Polymorphism, Restriction Fragment Length
- From: Chinese Journal of Experimental and Clinical Virology 2007;21(2):111-113
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the distribution of hepatitis B virus (HBV) genotype B subgenotype in China.
METHODSA cohort of 511 patients with chronic HBV genotype B infection, collected from 7 centers across China, were analyzed by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) or nucleotide sequencing.
RESULTSFor the 511 patients, only subgenotype Ba was identified and subgenotype Bj was not found.
CONCLUSIONIn China, subgenotype Ba was the most prevalent HBV strains, while subgenotype Bj was very rarely found.
