Comparison of NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 in detecting HIV-1 viral load.
- Author:
Pin-liang PAN
1
;
Wen-yan XU
;
Jun YAO
;
Xiao-xia TAO
;
Li-jian PEI
;
Yan JIANG
Author Information
- Publication Type:Journal Article
- MeSH: HIV Infections; virology; HIV-1; genetics; isolation & purification; Humans; Nucleic Acid Amplification Techniques; instrumentation; methods; RNA, Viral; genetics; Viral Load
- From: Chinese Journal of Experimental and Clinical Virology 2007;21(2):177-179
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the results of detecting HIV-1 load by using NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 assays.
METHODSEighty-two clinical samples were collected and HIV viral load was determined with the above-mentioned two methods.
RESULTSThe number of samples in which values obtained by NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 differed by <0.5 log10 RNA copies/ml and in which the viral load was undetectable accounted for 88.9 percent of the measures. The correlation coefficient between the two methods was 0.956 in 56 samples of Deltalog10 VL<0.5.
CONCLUSIONThe results of HIV-1 viral load determination with the two methods are highly comparable.
