Area specific differences in lung function indices and prevalence of airflow obstruction in adults: findings from people in 10 areas in China.

Fengling Lan; Jun Lyu; Yu Guo; Zheng Bian; Canqing YU; Huiyan Zhou; Yunlong Tan; Pei Pei; Weihua Cao; Email: Caoweihua60@163com; Junshi Chen; Zhengming Chen; Liming LI; Null

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Area specific differences in lung function indices and prevalence of airflow obstruction in adults: findings from people in 10 areas in China.

Author: Fengling LAN ¹ ; Jun LYU ¹ ; Yu GUO ² ; Zheng BIAN ² ; Canqing YU ¹ ; Huiyan ZHOU ² ; Yunlong TAN ² ; Pei PEI ² ; Weihua CAO ³ ; Email: CAOWEIHUA60@163.COM. ; Junshi CHEN ⁴ ; Zhengming CHEN ⁵ ; Liming LI ³ ; null
Author Information

1. Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
2. Chinese Academy of Medical Sciences.
3. Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
4. National Center for Food Safety Risk Assessment of China.
5. Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, UK.
Publication Type:Journal Article
MeSH: Adult; Aged; China; epidemiology; Female; Humans; Lung Diseases, Obstructive; epidemiology; Male; Middle Aged; Prevalence; Respiratory Function Tests; Surveys and Questionnaires
From: Chinese Journal of Epidemiology 2015;36(11):1205-1209
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo describe the area specific differences in lung function indices and prevalence of airflow obstruction (AFO) in adults found by China Kadoorie Biobank (CKB) study, involving 512 495 adults, in 10 areas in China.
METHODSThe detailed information on lung function indices (FEV, and FVC) and prevalence of AFO (diagnosed according to GOLD and LLN criteria) of subjects aged 30-79 years were analyzed, those with abnormal lung function indices at baseline survey were excluded.
RESULTSThe FEV1 and FVC among males (2.66 L, 3.16 L) were higher than those among females (1.99 L, 2.35 L). The FEV1 and FVC were highest in Henan and Harbin. The prevalence of AFO diaonosed according to GOLD criteria was 5.13% in males, higher than that in females (3.75%). The prevalence of AFO was higher in rural area than in urban area (males: 6.32% vs. 3.47%; females: 4.26% vs. 2.97%). The prevalence of AFO was highest in Sichuan (13.34% in males, 10.70% in females), followed by that in Suzhou, Henan and Hunan. The prevalence of AFO diagnosed according to LLN criteria (6.93% in males, 6.29% in females) was higher than that diagnosed according to GOLD criteria, but the area specific difference was similar.
CONCLUSIONThe lung function indices and the prevalence of AFO in adults varied greatly among the 10 areas covered by CKB study.