Cellular Schwannoma Arising in a Facial Nerve.
- Author:
Mee JOO
;
Hye Sung KIM
;
Yun Kyung KANG
;
Hye Kyung LEE
;
Jae Young PARK
- Publication Type:Case Report
- Keywords:
Cellular schwannoma;
Facial nerve;
S-100 protein
- MeSH:
Diagnostic Errors;
Facial Nerve*;
Mastoid;
Neurilemmoma*;
S100 Proteins
- From:Korean Journal of Pathology
1997;31(7):688-691
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cellular schwaninoma is a variant of schwannoma, which is characterized by predominance of cellular Antoni A area, presence of mitotic activity, nuclear hyperchromasia, pleomorphism, and absence of Verocay body. These pathologic features often prompted a misdiagnosis of malignancy. However, the clinical outcome has indicated the benignity of the tumor. We have experienced a case of cellular schwannoma arising from right facial nerve with right hemifacial weakness and erosion of mastoid process. Grossly, it was a 3.5 x 3 cm sized and relatively well encapsulated mass with yellowish, friable cut surface. Microscopically, cellular growth with moderate cellular pleomorphism and some mitotic activity (5/40 HPFS, up to 2/HPF) were noted. Immunostaining for S-100 protein showed diffuse strong positive reaction.
