Genetic polymorphism of fifteen short tandem repeat loci in Chinese Drungs.
- Author:
Jianghua LAI
1
;
Teng CHEN
;
Jidong FEN
;
Haibo ZHENG
;
Shengbin LI
Author Information
- Publication Type:Journal Article
- MeSH: Alleles; China; DNA; chemistry; genetics; Gene Frequency; Genotype; Humans; Polymorphism, Genetic; Sequence Analysis, DNA; Tandem Repeat Sequences; genetics
- From: Chinese Journal of Medical Genetics 2002;19(6):502-504
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the short tandem repeat (STR) polymorphism in Chinese Drungs (Tulungs).
METHODSThe genetic distributions of fifteen STR loci were investigated with the use of coamplification, genescan and genotype from 67 Drungs.
RESULTSThere were 144 STR alleles in Drung nationality, with their frequencies ranging from 0.0077 to 0.7846, heterozygosity(H) 0.3723-0.8639, discrimination power(DP) 0.5567-0.9548, probability of paternity exclusion(EPP) 0.2738-0.8358, polymorphism information content (PIC) 0.3461-0.8456 the accumulative DP 0.99999998 and EPP 0.99999894.
CONCLUSIONThe results of this study on the STR polymorphism in Chinese Drungs could be used as a basis for the genetic structure of Chinese ethnic groups and also be of significant application in anthropology and forensic science.
