Y-chromosome-specific microsatellite variation in Li ethnic groups of Hainan Island, China.
- Author:
Dong-na LI
1
;
Da-jun YING
;
Cai-ying OU
;
Lu CHEN
;
Zhen-jian ZHOU
;
Sheng-miao FU
Author Information
- Publication Type:Journal Article
- MeSH: China; Chromosomes, Human, Y; genetics; DNA; chemistry; genetics; Gene Frequency; Genetic Variation; Haplotypes; genetics; Humans; Male; Microsatellite Repeats; genetics; Sequence Analysis, DNA
- From: Chinese Journal of Medical Genetics 2003;20(1):46-48
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThe study was conducted to reveal the distribution of genetic polymorphism of four Y chromosome specific short tandem repeat (Y-specific STR) loci in Li ethnic groups in Hainan Island, China.
METHODSFour tetranucleotide STR loci were simultaneously amplified with fluorescently labeled primers, and genotypes were determined with an automated DNA sequencer.
RESULTSAmong 230 unrelated males, the alleles at the four Y-specific STR loci were composed of some complex repeat structure. 4,5,4,5 alleles were observed in loci DYS3891, DYS390, DYS391, DYS393 respectively. A set of human allele ladders for the typing of the four Y-specific STRs was obtained in Li ethnic population. Gene diversity index (D) and haplotype diversity data were estimated for the four Y-STRs.
CONCLUSIONThe preliminary study indicates a reference population for detecting male migration events and should be useful in population genetics and forensic applications.
