Gene frequencies of 4 STR loci in Tibetan population of Yunnan province.
- Author:
Bao-wen CHENG
1
;
Chun-jie XIAO
Author Information
- Publication Type:Journal Article
- MeSH: Alleles; China; DNA; genetics; Gene Frequency; Genotype; Humans; Lipoprotein Lipase; genetics; Polymerase Chain Reaction; methods; Tandem Repeat Sequences; genetics; Tibet; ethnology
- From: Chinese Journal of Medical Genetics 2003;20(1):84-85
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the gene frequencies of 4 STR loci in Tibetan population of Yunnan.
METHODSMultiple polymerase chain reaction (PCR), denaturing polyacrylamide gel electrophoresis and silver staining were used to detect D21S11, D8S1179, D16S539 and LPL loci. DNA samples collected from 105 unrelated Tibetan individuals in Yunnan province were analyzed.
RESULTSAt D21S11, D8S1179, D16S539 and LPL loci, 13, 8, 7, 6 alleles and 33, 21, 16 and 9 genotypes were observed, respectively. The genotype distribution of the 4 STR was in accordance with the Hardy-Weinberg equilibrium.
CONCLUSIONThe high combined discrimination power and exclusion power of the four loci in Tibetan population make multi-PCR detection a valuable tool for forensic identity, genetics and anthropology.
