Investigation of surgical managements of olfactory neuroblastoma
10.3321/j.issn:1673-0860.2008.02.003
- VernacularTitle:嗅神经母细胞瘤手术方法的探讨
- Author:
Liang-Yu LI
1
;
Lei CHEN
;
De-Liang HUANG
;
Rong-Guang WANG
;
Dong-Yi HAN
;
Wei-Yan YANG
Author Information
1. 解放军总医院
- Keywords:
Endoscopy;
Esthesioneuroblastoma,olfactory;
Otorhinolaryngologic surgical procedures
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2008;43(2):89-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety and efficacy of transnasal endoscopic resection and eraniofacial resection through an external approach for olfactory neuroblastoma(ONB).Methods Thirty two Patients With ONB treated between 1987 and 2006 were retrospectively reviewed.Results The patients were followed up for 8-135 months,the median follow-up time was 20 months.The longest followe-up time of Patients treated by endoscope was 79 months,and patients treated by combined endoscope and transcranial surgery was 87 months.At Kadish stage B the 3-year survival rate of patients with transnasal endoscopic resection was 78.8% and at Kadish stage C it was 50.0%.At Kadish stage B the 3-year survival rate of patients with craniofacial resection through an external approach was 60.0% and at Kadish stage C it Was 44.4%.The bleeding amounts in above two approaches were 140 ml and 450 m1.The average length of stay in hospital in ransnasal endoscopic resection approach was markedly reduced(P<0.01).Conclusions Olfactory neuroblastoma Can be safely and effectively excised and reconstructed endoscopieally with comparable degrees of tissue removal as with external approaches.The time of stay in hospital Can be reduced and the surgical trauma can be diminished.
