Sonographically guided percutaneous ethanol injection for therapy of thyroid benign lesion
10.3321/j.issn:1673-0860.2008.06.007
- VernacularTitle:超声引导下经皮穿刺注射无水乙醇治疗甲状腺良性病变
- Author:
Li-Juan NIU
1
;
Hong-Lin LI
;
Zheng-Jiang LI
;
Ping-Zhang TANG
Author Information
1. 中国医学科学院肿瘤医院
- Keywords:
Thyroid neoplasms;
Uhrasonography;
Ethanol
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2008;43(6):428-431
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop the microtrauma therapy for thyroid benign lesion.to evaluate efficacy of sonographically guided percutaneous ethanol injection for therapy of thyroid benign lesion.Methods Thirty-two patients with thvroid benign lesion were treated in Cancer Hospital.tlle patients had thyroid disease with cystic or cystic and solid nodule without heart and lung disease.and no allergy to ethanol,but the most diameter was below 3 cm for the solid disease.These patients were divided into two groups,the first group were 14 patients(from June 2002 to August 2003),the second group was 18 patients (from September 2003 to March 2006).The mean injeetion times was four (1-6) in the first group.the volume of each ethanol iniection made the absolute ethanol well-distributed and kept slight compression intra.lesion for five minutes for solid disease.Paaial liquid was extracted for cystic disease first.and 2-10 ml ethanol was injected into cyst,the internal time between two punctures was one week.Each patient received six times ethanol injection in the second group,ethanol injection wag 8ame with the first group.The mean follow-up was 29 (12-57) months.Results The efficacy rate was 100.O%,the cure rate was 69.2%in the first group.The efficacy rate was 100.0%,the cure rate was 77.8% in the second group.There was no significant difference in the cure rate between the groups(X2=0.0258,P>0.05).During follow-up,ultrasound revealed no recurrence for the cured patients and no growth for tlle remnant lesion.Its complications were transient after the procedure,no severe eomplications occurred. Conclusions Sonographically guided percutaneous ethanol injection should be simple,effective,and safe for the thyroid benign lesion,it is easy popularized and may has the effect of cosmetology and microtrauma.
