Development and Validation of the Korean Version of Hand-Foot Skin Reaction and Quality of Life Questionnaire (HF-QoL-K).
10.3346/jkms.2016.31.12.1969
- Author:
Se Hyun NAM
1
;
Hyun Jin CHOI
;
Woo Dae KANG
;
Seok Mo KIM
;
Myong Cheol LIM
;
Sang Yoon PARK
;
Jung Sup KIM
;
Byoung Gie KIM
;
Duk Soo BAE
;
Jeong won LEE
;
Tae Joong KIM
;
Taejong SONG
Author Information
1. Department of Obstetrics and Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. taejong.song@gmail.com
- Publication Type:Original Article
- Keywords:
Hand-Foot Syndrome;
Quality of Life;
Questionnaires;
Validation;
Gynecologic Cancer;
Chemotherapy
- MeSH:
Drug Therapy;
Hand-Foot Syndrome;
Humans;
Quality of Life*;
Reproducibility of Results;
Skin*
- From:Journal of Korean Medical Science
2016;31(12):1969-1975
- CountryRepublic of Korea
- Language:English
-
Abstract:
Given the growing number of cancer patients and the resulting increase in the administration of chemotherapeutic agents, convenient and effective methods for measuring the symptoms and quality of life associated with the hand-foot syndrome (HFS) are needed. Therefore, the aim of this study was to develop and validate the Korean version of the hand-foot skin reaction and quality of life questionnaire (HF-QoL-K), comprising a 20-item symptom domain and an 18-item daily activity domain. After we developed the HF-QoL-K, 209 Korean patients with gynecologic cancer who were undergoing chemotherapeutic agents relating the HFS were asked to fill in the questionnaire. The content validity, internal consistency reliability, and test-retest reliability were evaluated. The internal validity index, Cronbach’s alpha coefficient, and intra-class correlation coefficient of the HF-QoL-K were 0.90, 0.958, and 0.825 (95% confidence interval [CI], 0.774–0.865), respectively. The scatter plot (Pearson correlation coefficient, 0.826) and the Bland-Altman plot for test-retest reliability were also acceptable. The HF-QoL-K instrument is a valid and reliable questionnaire for the measurement of the symptoms and quality of life in Korean cancer patients suffering HFS.
