Some remarks of age and karyotypes of parents. WHO have had children with down’s syndrome
- Author:
Ruc Van Nguyen
- Publication Type:Journal Article
- Keywords:
down's syndrome
- MeSH:
Down Syndrome;
diagnosis
- From:Journal of Medical Research
1998;7(3):21-24
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The total 76 children from one month of age to fourteen years of age have been determined as phenotypic features and karyotypes of Down's syndrome. The distribution is as follow: typical trisomy is 69 cases (90%), translocation is 4 cases (5.26%), mosaism is 3 cases (3.95%). The mean maternal age at the birth of Down's patients was 30.8±2.2. The mean paternal age at the birth of Down's patients was 33.9±1.7. Maternal age distribution at the birth of Down's patients: The frequency was lowest in the mothers under 20 years old. It increases at age 25-29, then it decreased and increased again after the age 35-39. Chromosome studies have been made also on the patients, whose karyotypes are all normal (46,XX or 46,XY). The pedigrees of all patients were made. It has no one who has two patients in the same family
