Evolution of Endovascular Therapy in Acute Stroke: Implications of Device Development.
10.5853/jos.2015.17.2.127
- Author:
Adithya BALASUBRAMAIAN
1
;
Peter MITCHELL
;
Richard DOWLING
;
Bernard YAN
Author Information
1. Comprehensive Stroke Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia. bernard.yan@mh.org.au
- Publication Type:Review
- Keywords:
Mechanical Thrombectomy;
Acute Ishemic Stroke;
Clot Retrieval;
Endovascular;
Stentriever
- MeSH:
Arteries;
Hand;
Patient Selection;
Stroke*
- From:Journal of Stroke
2015;17(2):127-137
- CountryRepublic of Korea
- Language:English
-
Abstract:
Intravenous thrombolysis is an effective treatment for acute ischaemic stroke. However, vascular recanalization rates remain poor especially in the setting of large artery occlusion. On the other hand, endovascular intra-arterial therapy addresses this issue with superior recanalization rates compared with intravenous thrombolysis. Although previous randomized controlled studies of intra-arterial therapy failed to demonstrate superiority, the failings may be attributed to a combination of inferior intra-arterial devices and suboptimal selection criteria. The recent results of several randomized controlled trials have demonstrated significantly improved outcomes, underpinning the advantage of newer intra-arterial devices and superior recanalization rates, leading to renewed interest in establishing intra-arterial therapy as the gold standard for acute ischaemic stroke. The aim of this review is to outline the history and development of different intra-arterial devices and future directions in research.
