Effect of purple sweet potato on lipid metabolism and oxidative stress in hyperlipidemic rats.
- Author:
Wei-ping CHEN
1
;
Tong-jun MAO
;
Lin FAN
;
Yu-han ZHOU
;
Jing YU
;
Yun JIN
;
Peng-chao HOU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Disease Models, Animal; Hyperlipidemias; metabolism; Ipomoea batatas; Lipid Metabolism; Lipids; blood; Male; Oxidative Stress; drug effects; Rats; Rats, Sprague-Dawley
- From: Journal of Zhejiang University. Medical sciences 2011;40(4):360-364
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of purple sweet potato on lipid metabolism and oxidative stress in hyperlipidemic rats.
METHODSForty male SD rats were randomly divided into 4 groups: normal control group, high-fat control group, high purple sweet potato groups, low purple sweet potato group. The rats were fed with different diets for 6w respectively.
RESULTSSerum TC, TG levels were significantly lower in high dosage group than in high-fat control group; while only serum TG was significantly lower in low dosage group than in high-fat control group, these changes started at the third week and lasted to the end of experiment. Serum LDL-C and AI levels were significantly lower in high and low dosage group than in high-fat control group, whereas, serum HDL-C was significantly higher than that in high-fat control group at w3 and lasted to the end of experiment. Serum SOD was significantly higher in high and low dosage group than in high-fat control group, whereas, serum MDA was significantly lower than that in high-fat control group at w6.
CONCLUSIONPurple sweet potato can decrease serum lipids and reduce hepatic oxidative stress in hyperlipidemic rats.
