Effect of purple sweet potato flavonoids on metabolism of glucose and lipids in diabetic rats.
- Author:
Hui-fang JIANG
1
;
Xiang-rong LI
;
Chao TANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Glucose; metabolism; Diabetes Mellitus, Experimental; blood; drug therapy; Flavonoids; pharmacology; Ipomoea batatas; chemistry; Lipids; blood; Male; Rats; Rats, Sprague-Dawley
- From: Journal of Zhejiang University. Medical sciences 2011;40(4):374-379
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effects of purple sweet potato flavonoids (PSPF) on blood glucose and lipids levels in diabetic rats.
METHODSDiabetes was induced by intraperitoneal injection of streptozotocin (STZ, 65 mg.kg(-1)) in rats. The changes of fasting blood glucose and lipids levels in serum and body weight, food and fluid intake of diabetic rats treated with PSPF were examined.
RESULTSDiabetic symptoms were ameliorated after rats were fed with PSPF. The fasting blood glucose (FBG), GSP, TC, TG, LDL-C were decreased and serum HDL-C levels were increased (P<0.01) in high, medium dose PSPF groups; while FBG, serum GSP, TG, LDL-C were also improved in low dose group (P<0.05 or P<0.01).
CONCLUSIONPurple sweet potato flavonoids can decrease the blood glucose and lipids levels in diabetic rats.
