Aortic elastic properties and its clinical significance in intracranial aneurysms.
- Author:
Zhao-xia PU
1
;
Xiang-dong YOU
;
Wen-chao WENG
;
Jian-an WANG
;
Jian SHI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aorta; diagnostic imaging; physiopathology; Case-Control Studies; Elasticity; Female; Humans; Intracranial Aneurysm; physiopathology; Male; Middle Aged; Ultrasonography
- From: Journal of Zhejiang University. Medical sciences 2011;40(5):550-554
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the aortic elastic properties and its clinical significance in intracranial aneurysms (IAs).
METHODSOne hundred and seven IAs patients (57 with hypertension) and 108 healthy subjects were recruited. The internal aortic diameters in systole and diastole were measured by the M-mode echocardiography, the aortic elasticity indexes were calculated and compared.
RESULTSThe aortic distensibility (DIS) was lower and the aortic stiffness index (SI) was higher in IAs patients than those in controls (both P <0.001). DIS was lower and SI was higher in IAs patients with hypertension (IAs-HP) than those in IAs with no hypertension (P <0.001). Similar results were obtained when the aortic elasticity index were adjusted for body surface area and body mass index.
CONCLUSIONAbnormal aortic elasticity is a common finding in IAs patients and hypertension is closely related to the severity of aortic elasticity.
