Polysaccharides activate signaling pathways of macrophage.
- Author:
Zhi-xin MA
1
;
Lu-hang ZHAO
Author Information
1. Department of Biochemistry and Genetics, Zhejiang University School of Mecicine, Hangzhou, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Macrophage Activation;
drug effects;
immunology;
Macrophages;
drug effects;
immunology;
metabolism;
Polysaccharides;
pharmacology;
Signal Transduction
- From:
Journal of Zhejiang University. Medical sciences
2011;40(5):567-572
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharides extracted from various sources are natural active substances, which may lead to the activation of macrophage via multiple pathways and mechanisms. This article intends to illustrate the signaling pathways of polysaccharides from plants, fungi, algae and other sources, to identify the mechanisms on the molecular level, and to explore the novel target immunomodulatory agents.