Association of Helicobacter pylori infection and serum homocysteine level in patients with cerebral infarction.
- Author:
Hai-qin WU
1
;
Xin ZHANG
;
Yan TANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Cerebral Infarction; blood; complications; Female; Helicobacter Infections; blood; complications; Helicobacter pylori; Homocysteine; blood; Humans; Male; Middle Aged
- From: Journal of Zhejiang University. Medical sciences 2012;41(1):89-92
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the association of Helicobacter pylori infection and serum homocysteine(Hcy) levels with acute cerebral infarction.
METHODSSerum Hp-IgG, Hp-CagA-IgG and Hcy were detected by biological micro-array analysis system in 85 patients with acute cerebral infarction and 40 healthy subjects (control group).
RESULTSThe positive rates of Hp-IgG and Hp-CagA-IgG significantly increased in cerebral infarction group compared with controls (P<0.05). There were significant differences in serum Hcy level between Hp-CagA-IgG positive and negative patients (P<0.05), but not between Hp-IgG positive and negative patients (P>0.05).
CONCLUSIONCagA-positive Hp infection may increase the risk of cerebral infarction, which might be associated with the increased serum homocysteine level.
