Histological subtypes of lung cancer in Chinese males from 2000 to 2012.

Xiao Nong Zou; Dong Mei Lin; Xia Wan; Ann Chao; Qin Fu Feng; Zhen Dai; Gong Huan Yang; Ning LV

Return

Histological subtypes of lung cancer in Chinese males from 2000 to 2012.

Author: Xiao Nong ZOU ¹ ; Dong Mei LIN ² ; Xia WAN ³ ; Ann CHAO ⁴ ; Qin Fu FENG ⁵ ; Zhen DAI ¹ ; Gong Huan YANG ³ ; Ning LV ²
Author Information

1. National Office of Cancer Prevention and Control, Cancer Institute/Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
2. Department of Pathology, Chinese Academy of Medical Sciences, Beijing 100021, China.
3. Center for Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China.
4. Center for Global Health, National Cancer Institute, Bethesda MD, USA.
5. Department of Radiation Oncology, Chinese Academy of Medical Sciences, Beijing 100021, China.
Publication Type:Journal Article
Keywords: Epidemiology; Histology; Lung cancer
MeSH: Adult; Aged; Aging; Carcinoid Tumor; epidemiology; etiology; Carcinoma, Adenosquamous; epidemiology; etiology; China; epidemiology; Humans; Lung Neoplasms; classification; epidemiology; etiology; Male; Middle Aged; Smoking; adverse effects; Time Factors
From: Biomedical and Environmental Sciences 2014;27(1):3-9
CountryChina
Language:English
Abstract:
OBJECTIVETo characterize the histological and epidemiological features of male lung cancer patients in China.
METHODSThe demographic and histological information about male lung cancer patients identified from 2000-01-01 to 2012-12-31, was collected from the Cancer Hospital of the Chinese Academy of Medical Sciences. Relative frequencies (RF) were estimated for major histological subtypes and compared according to the years of diagnosis and birth.
RESULTSThe RF of adenocarcinoma (ADC) increased from 21.96% to 43.36% and the RF of squamous cell carcinoma (SCC) decreased from 39.11% to 32.23% from 2000 to 2012 in the 15 427 male lung cancer patients included in this study (Z=17.909, P<0.0001; Z=-6.117, P<0.0001). The RF of ADC increased from 28.72% in 2000-2004, 36.88% in 2005-2008 to 48.61% in 2009-2012 in patients born after 1960. The age-adjusted RF of ADC in 2007-2012 increased consistently in all the investigated areas.
CONCLUSIONThe increased RF of ADC in male lung cancer patients highlights the need for further investigation of the etiologic factors of these tumors. Smoke-free policies rather than modifying tobacco products should be enforced.