Dyslipidemia and outcome in patients with acute ischemic stroke.
- Author:
Tian XU
1
;
Jin Tao ZHANG
2
;
Mei YANG
3
;
Huan ZHANG
1
;
Wen Qing LIU
2
;
Yan KONG
2
;
Tan XU
1
;
Yong Hong ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Acute ischemic stroke; Dyslipidemia; Multivariate logistic regression analysis; Outcome; Propensity score-adjusted analysis
- MeSH: Aged; Aged, 80 and over; Brain Infarction; blood; complications; mortality; China; epidemiology; Cholesterol; blood; Dyslipidemias; complications; Female; Humans; Male; Middle Aged
- From: Biomedical and Environmental Sciences 2014;27(2):106-110
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo study the relationship between dyslipidemia and outcome in patients with acute ischemic stroke.
METHODSData about 1 568 patients with acute ischemic stroke were collected from 4 hospitals in Shandong Province from January 2006 to December 2008. National Institute of Health Stroke Scale (NIHSS) >10 at discharge or death was defined as the outcome. Effect of dyslipidemia on outcome in patients with acute ischemic stroke was analyzed by multivariate logistic regression analysis and propensity score-adjusted analysis, respectively.
RESULTSThe serum levels of TC, LDL-C, and HDL-C were significantly associated with the outcome in patients with acute ischemic stroke. Multivariate logistic regression analysis and propensity score-adjusted analysis showed that the ORs and 95% CIs were 3.013 (1.259, 7.214)/2.655 (1.298, 5.43), 3.157 (1.306, 7.631)/3.405 (1.621, 7.154), and 0.482 (0.245, 0.946)/0.51 (0.282, 0.921), respectively, for patients with acute ischemic stroke. Hosmer-Lemeshow goodness-of-fit test showed no significant difference in observed and predicted risk in patients with acute ischemic stroke (chi-square=8.235, P=0.411).
CONCLUSIONSerum levels of TC, LDL-C, and HDL-C are positively related with the outcome in patients with acute ischemic stroke.
