Determination of DNA of hepatitis B virus in the serum by PCR
- Author:
Lien Thi Minh Trinh
- Publication Type:Journal Article
- Keywords:
DNA of hepatitis B virus
- MeSH:
DNA;
Hepatitis B virus;
serum;
Polymerase Chain Reaction
- From:Journal of Practical Medicine
2001;395(3):26-29
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
31 samples of sera from patients with hepatitis B or chronic hepatitis in Japan, were divided into 3 groups according to the status of HBsAg and HBeAg and implemented the PCR. The results have shown that PCR was more sensitive and specific than DNA diagnosis. The PCR can detect serum HBV DNA in the almost of patients with HBeAg (+). The serum samples with low efficacy of HBeAg or nagative HBeAg and negative HBVDNA showed the normal level of ALT at the same time.