CD36 Antigen Deficiency and Platelet Transfusion.
10.7534/j.issn.1009-2137.2016.03.055
- Author:
Hai-Yan LI
1
;
Yan ZHOU
1
;
Wei-Dong SHEN
2
Author Information
1. Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning 530007, Guangxi Province, China.
2. Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning 530007, Guangxi Province, China. E-mail: nanningshenweidong@163.com.
- Publication Type:Journal Article
- MeSH:
Autoantibodies;
blood;
Blood Platelet Disorders;
Blood Platelets;
Blood Transfusion;
CD36 Antigens;
deficiency;
Female;
Genetic Diseases, Inborn;
Histocompatibility;
Humans;
Platelet Transfusion;
Pregnancy
- From:
Journal of Experimental Hematology
2016;24(3):934-938
- CountryChina
- Language:Chinese
-
Abstract:
CD36 is a transmembrane glycoprotein, a multi-ligand receptor, possesses various biological functions. CD36 deficiency may stimulate the body to produce anti-CD36 alloimmune antibodies through the several pathways, such as blood transfusion, pregnancy or organ transplantation and so on, leading to the refractoriness of immune platelet transfusion and other diseases. The recent research advances of CD36 deficiency and its molecular biological basis, platelet transfusion and CD36 antibody detection are summarized briefey in this review.
