Quantifying the amplitude of microvolt T wave alternans with sparse principal component analysis.
- Author:
Kui XIANG
1
;
Bingnan LI
Author Information
1. School of Automation, Wuhan University of Technology, Wuhan 430070, China. xkarcher@126.com
- Publication Type:Journal Article
- MeSH:
Algorithms;
Arrhythmias, Cardiac;
diagnosis;
physiopathology;
Death, Sudden, Cardiac;
prevention & control;
Electrocardiography;
methods;
Humans;
Principal Component Analysis;
Signal Processing, Computer-Assisted
- From:
Journal of Biomedical Engineering
2012;29(5):954-982
- CountryChina
- Language:Chinese
-
Abstract:
T wave alternans in ECG is an important prediction factor for a sudden death. It is crucial in clinic to quantify the amplitude of T wave alternans. However, T wave alternans are highly non-stationary, which makes accurate quantification very difficult. In this study, we proposed a new method to improve the amplitude quantification. We identified T wave alternans by principal component analysis (PCA) with statistical test, and processed the principal components with T wave alternans further by imposing sparse constraint. We evaluated and compared our method against other 4 popular solutions on an international benchmark database. The results including rank correlation coefficient and relative error indicate that this sparse principal component (SPC) based method is better than others.
