Research progresses of paracrine effect of bone marrow derived mesenchymal stem cells on wound healing.
- Author:
Qing LUO
1
;
Chen ZHANG
;
Guanbin SONG
Author Information
1. Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 40044, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Bone Marrow Cells;
cytology;
physiology;
Cell Differentiation;
physiology;
Cells, Cultured;
Humans;
Mesenchymal Stromal Cells;
cytology;
physiology;
Paracrine Communication;
physiology;
Wound Healing;
physiology
- From:
Journal of Biomedical Engineering
2012;29(5):999-1002
- CountryChina
- Language:Chinese
-
Abstract:
Bone marrow derived mesenchymal stem cell (BMSC) is one of the crucial cell types which plays roles in wound healing of tissues. In the last decades, it was believed that BMSCs promoted wound healing by differentiating into multiple lineages and placing the wounded tissues. In recent years, a new viewpoint arose from evidences that the paracrine effect of BMSCs might play a more important role in the process of wound healing than differentiation. Understanding the role of BMSCs paracrine in wound healing would be vital to clarify the mechanism how BMSCs take part into the process of wound healing. In this paper, we review the new research processes of BMSCs paracrine in wound healing of tissues.
