The Use of Cultured Allogenic Keratinocyte Grafting in a Patient with Epidermolysis Bullosa Simplex.
10.5021/ad.2011.23.S3.S393
- Author:
Kee Cheol SHIN
1
;
Bo Young PARK
;
Han Koo KIM
;
Woo Seob KIM
;
Tae Hui BAE
Author Information
1. Department of Plastic and Reconstructive Surgery, Chung-Ang University Hospital, Seoul, Korea. hkkiim@cau.ac.kr
- Publication Type:Case Report
- Keywords:
Epidermolysis bullosa simplex;
Keratinocyte
- MeSH:
Blister;
Cicatrix;
Epidermolysis Bullosa;
Epidermolysis Bullosa Simplex;
Humans;
Infant, Newborn;
Keratinocytes;
Methylmethacrylates;
Polystyrenes;
Skin;
Skin Transplantation;
Transplants
- From:Annals of Dermatology
2011;23(Suppl 3):S393-S397
- CountryRepublic of Korea
- Language:English
-
Abstract:
Epidermolysis bullosa (EB) is a rare genetic disease that is known for continuous skin blistering caused by minor trauma. The skin blisters and bullae that develop often cause skin defects. There is no definitive treatment for EB, only symptomatic relief. We report our experience with cultured allogenic keratinocyte grafting in a newborn patient with EB simplex who had unhealed raw surfaces and was not a skin grafting candidate. The skin lesions of the patient were covered with cultured allogenic keratinocyte grafts and re-epithelialized quickly with no scarring. Allogenic keratinocyte grafting reduced pain and produced noticeable improvements in the unhealed wounds. We think that allogenic keratinocyte grafting can play an important role in the management of patients with EB simplex.
