A case-control study on the risk factors of leukemia in mining areas of rare-earth in South Jiangxi.
- Author:
Lei WU
1
;
Yue-Ping ZHOU
;
Hong-Jing ZHONG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Case-Control Studies; Child; Child, Preschool; Female; Humans; Insecticides; toxicity; Leukemia; etiology; Logistic Models; Male; Metals, Rare Earth; toxicity; Middle Aged; Mining; Organophosphorus Compounds; Risk Factors; Tea; Water Pollutants, Chemical; toxicity
- From: Chinese Journal of Epidemiology 2003;24(10):879-882
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEIn order to explore the correlation on radioactive contamination of lanthanon to leukemia, and provide clues for the causes and prevention of leukemia in mining areas of rare-earth elements.
METHODS1:1 matched case-control study was used. A total of 51 clinically confirmed leukemia cases, individually matched with controls from general population, were interviewed in mining areas of rare-earth in South Jiangxi from November to December, 2001. Data were analyzed, using conditional logistic regression.
RESULTSThe main risk factors would include frequently drinking water from river (OR = 5.543), distance from residence to rare-earth mine and years for living in the area (OR = 3.308), exposure to organophosphorus pesticide (OR = 3.014). Tea drinking habit appeared to be a protective factor.
CONCLUSIONSLeukemia seemed to be related to environmental pollution with rare-earth elements around the residential areas and organophosphorus pesticide exposure. The protective factor of tea drinking habit seemed to be unique in this study, which called for further studies.
