Surveillance of healthy people's Japanese encephalitis neutralizing antibody in some areas of Henan Province
10.3760/cma.j.issn.1003-9279.2011.06.001
- VernacularTitle:河南省部分地区健康人群流行性乙型脑炎病毒中和抗体监测
- Author:
Xiao-Yan TANG
1
;
Hong-Xia MA
;
Chao XU
;
Si-Yuan SHANG
;
Kai KANG
;
Xue-Yong HUANG
;
Zun-Dong YIN
;
Huan-Yu WANG
Author Information
1. 河南省疾病预防控制中心
- Keywords:
Encephalitis,Japanese;
Antibodies,viral;
Monitoring,immunologic
- From:
Chinese Journal of Experimental and Clinical Virology
2011;25(6):401-404
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the prevalence characteristics and influence factors of Japanese encephalitis(JE) neutralizing antibody in healthy people.Methods Xinyang and Luoyang is the two cities in Henan Province.In 2010,healthy people of these two cities were selected by random sampling method to eight age groups:less than one year old,1 - 2 years old,3 - 4,5 - 6,7 - 14,15 - 19,20 - 59,and above 60 years old,their blood specimens were collected in May before JE infection and in November after JE infection,then followed with epidemiological investigation for JE neutralizing antibody by MCPENT.Results 519 healthy people were surveyed,1008 effective blood specimens were collected and tested.The JE neutralizing antibody positive rate was 59.52％ in men,and 67.39％ in male,these two rates had no statistical significance (x2=3.41,P ＞ 0.05 ).The JE neutralizing antibody was 58.66％ in May,and 61.20％ in November,these two rates had no statistical significance (x2 =0.68,P ＞ 0.05).The JE neutralizing antibody positive rate of 0 - 14 years old age group was 55.19％ in Xinyang,and 45.03％ in Luoyang,these two rates had no statistical significance(x2 =3.53,P ＞ 0.05 ).The JE neutralizing antibody positive rate of above 15 years old age group is 97.78％ in Xinyang,and 48.94％ in Luoyang,these two rates had statistical significance (x2 =55.42,P ＜ 0.05).The JE neutralizing antibody positive rate of JE vaccination was 56.85％,and 38.35 ％ in no JE vaccination,these two rates had statistical significance(x 2=10.88,P ＜ 0.05 ).Conclusion The JE neutralizing antibody positive rate was showing significant differences in people above 15 years old between Xinyang and Luoyang.The JE neutralizing antibody positive rate was showing significant differences between.JE vaccination and no vaccination.Xinyang and Luoyang City,recommended strengthening the 0 -14 year-olds immunized,and at the same time,exploring and paying attention to JE immunization strategy of people above 15 years old in Luoyang.
