Different active ingredients of medicinal plant based on function differentiation of homologous gene.
- Author:
Yuan YUAN
;
Jun YU
;
Lu-qi HUANG
;
Xu-min WANG
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
analysis;
Gene Duplication;
Plant Proteins;
genetics;
Plants, Medicinal;
chemistry;
genetics;
Quality Control
- From:
China Journal of Chinese Materia Medica
2015;40(6):1023-1026
- CountryChina
- Language:Chinese
-
Abstract:
In the research field of quality control in Chinese medicinal materials, variation in active ingredients of medicinal plant is always the key and hot issues. With the development of high-throughput sequencing technologies and reducing cost, a large numbers of genes from medicinal plant were cloning and provide a solid foundation for further research of gene structure and its biological function, and also provides conditions for explore active ingredient variation and its quality control from the perspective of molecular pharmacognosy. This paper introduces the concept of homologous gene, gene duplication and classification. We prospect the function of duplicated genes in the role of molecular mechanism research about variation in active ingredients, aiming at providing a new way for medicinal materials quality control.
