Progresses in screening active compounds from herbal medicine by affinity chromatography.
- Author:
Ying-shu FENG
;
Shan-shan TONG
;
Xi-ming XU
;
Jiang-nan YU
- Publication Type:Journal Article
- MeSH:
Animals;
Chromatography, Affinity;
methods;
trends;
Drug Evaluation, Preclinical;
methods;
trends;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
pharmacology;
Humans;
Plants, Medicinal;
chemistry
- From:
China Journal of Chinese Materia Medica
2015;40(6):1032-1037
- CountryChina
- Language:Chinese
-
Abstract:
Affinity chromatography is a chromatographic method for separating molecules using the binding characteristics of the stationary phase with potential drug molecules. This method can be performed as a high throughput screening method and a chromatographic separation method to screen a variety of active drugs. This paper summarizes the history of affinity chromatography, screening technology of affinity chromatography, and application of affinity chromatography in screening bio-active compounds in herbal medicines, and then discusses its application prospects, in order to broaden applications of the affinity chromatography in drug screening.
