Application of supercritical solution rapid expansion technology in preparation of fine pharmacal particles.
- Author:
Zhong-yi ZHANG
1
;
Hong-lei LI
;
Zheng-jie LEI
Author Information
1. Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. zhang43499@sohu.com
- Publication Type:Journal Article
- MeSH:
Crystallization;
methods;
Delayed-Action Preparations;
Nanostructures;
Particle Size;
Pharmaceutical Preparations;
chemistry;
Solubility;
Solutions;
Technology, Pharmaceutical;
instrumentation;
methods;
Temperature
- From:
China Journal of Chinese Materia Medica
2006;31(23):1933-1936
- CountryChina
- Language:Chinese
-
Abstract:
Rapid expansion of supercritical solution (RESS), a new technology, has been developed in the recent years. Fundamental principle of RESS technology used to prepare fine pharmacal particles was summarized in this paper. A brief review of factors which influenced the process of RESS and application of RESS technology were introduced.